The Brick Testament
(not necessarily worksafe, and occasionally has lego characters doing naughty things.)

Flyguy
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whimsical, peaceful, neat

The Mystical Ball
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It reads your mind! Figuring this thing out is only half the fun; the other half is using it to freak out others who can't.

365 Tomorrows
a daily bite-sized dose of intense imagination

My favorite online comic (starting at the beginning! the plot is vital!):

It's mostly character development until the subplots hit their stride here.

Bubblewrap!
requires flash

EPIC 2014
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I love creative names. But even these make me blink in awe:
The Utah Baby Namer

Really compelling and honest writing:
A Year of Living Stupidly

Never ceases to amuse: Weight Watchers recipe cards from 1974

Mean tech humor. It's how we stay sane, people.

The 213 Things Skippy Isn't Allowed To Do in the US Army

And a handful of tributes

When in doubt, there are always Apple Trailers.
requires quicktime

Engrish.com is... just so funny.

Mr. Picasso Head
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Stumble Upon (for Firefox):

Circular Lives
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All hail Foamy.
requires flash